# Setup and usage instructions for the Welsh Advanced Neuroimaging Database (WAND)
**Carolyn Beth McNabb<sup>1</sup>, Ian D Driver<sup>1</sup>, Vanessa Hyde<sup>1</sup>, Garin Hughes<sup>1</sup>, Hannah Louise Chandler<sup>1</sup>, Hannah Thomas<sup>1</sup>, Eirini Messaritaki<sup>1</sup>, Carl Hodgetts<sup>2</sup>, Craig Hedge<sup>3</sup>, Christopher Allen<sup>4</sup>, Maria Engel<sup>1</sup>, Sophie Felicity Standen<sup>1</sup>, Emma Morgan<sup>1</sup>, Elena Stylianopoulou<sup>1</sup>, Svetla Manolova<sup>1</sup>, Lucie Reed<sup>1</sup>, Mark Drakesmith<sup>1</sup>, Michael Germuska<sup>1</sup>, Alexander Shaw<sup>5</sup>, Lars Mueller<sup>6</sup>, Holly Rossiter<sup>1</sup>, Christopher Davies-Jenkins<sup>7</sup>, John Evans<sup>1</sup>, David Owen<sup>1</sup>, Gavin Perry<sup>1</sup>, Slawomir Kusmir<sup>1,8</sup>, Emily Lambe<sup>1</sup>, Adam Partridge<sup>1</sup>, Alison Cooper<sup>1</sup>, Peter Hobden<sup>1</sup>, Andrew Lawrence<sup>1</sup>, Richard Wise<sup>9</sup>, James Walters<sup>10</sup>, Petroc Sumner<sup>1</sup>, Krish Singh<sup>1</sup>, and Derek K Jones<sup>1</sup>**
**Carolyn Beth McNabb<sup>1</sup>, Ian D Driver<sup>1</sup>, Vanessa Hyde<sup>1</sup>, Garin Hughes<sup>1</sup>, Hannah Louise Chandler<sup>1</sup>, Hannah Thomas<sup>1</sup>, Eirini Messaritaki<sup>1</sup>, Carl Hodgetts<sup>1,2</sup>, Craig Hedge<sup>3</sup>, Christopher Allen<sup>4</sup>, Maria Engel<sup>1</sup>, Sophie Felicity Standen<sup>1</sup>, Emma L Morgan<sup>1</sup>, Elena Stylianopoulou<sup>1</sup>, Svetla Manolova<sup>1</sup>, Lucie Reed<sup>1</sup>, Mark Drakesmith<sup>1</sup>, Michael Germuska<sup>1</sup>, Alexander D Shaw<sup>5</sup>, Lars Mueller<sup>6</sup>, Holly Rossiter<sup>1</sup>, Christopher W Davies-Jenkins<sup>7,8</sup>, Tom Lancaster <sup>9</sup>, John Evans<sup>1</sup>, David Owen<sup>1</sup>, Gavin Perry<sup>1</sup>, Slawomir Kusmia<sup>1,10</sup>, Emily Lambe<sup>1</sup>, Adam M Partridge<sup>1</sup>, Alison Cooper<sup>1</sup>, Peter Hobden<sup>1</sup>, Hanzhang Lu<sup>7,8</sup>, Kim S Graham<sup>1,12</sup>, Andrew D Lawrence<sup>1,12</sup>, Richard Wise<sup>1,13,14</sup>, James Walters<sup>15</sup>, Petroc Sumner<sup>1</sup>, Krish D Singh<sup>1</sup>, and Derek K Jones<sup>1</sup>**
<sup>1</sup>Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, United Kingdom,
<sup>2</sup>Department of Psychology, Royal Holloway, University of London, Egham, United Kingdom,
<sup>3</sup>School of Psychology, Aston University, Birmingham, United Kingdom,
<sup>4</sup>Department of Psychology, Durham University, Durham, United Kingdom,
<sup>5</sup>Washington Singer Laboratories, University of Exeter, Exeter, United Kingdom,
<sup>6</sup>Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom,
<sup>7</sup>The Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA,
<sup>8</sup>F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Kreiger Institute, Baltimore, Maryland, USA,
<sup>9</sup>Department of Psychology, University of Bath, Bath, United Kingdom,
<sup>10</sup>IBM Polska Sp. z o. o., Department of Content Design, Cracow, Poland
<sup>11</sup>University of Sheffield, Research Services, New Spring House, 231 Glossop Road, Sheffield, S10 2GW, UK
<sup>12</sup>School of Philosophy, Psychology and Language Sciences, Dugald Stewart Building, University of Edinburgh, 3 Charles Street, Edinburgh, EH8 9AD, UK
<sup>13</sup>Department of Neurosciences, Imaging, and Clinical Sciences, 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy,
<sup>14</sup>Institute for Advanced Biomedical Technologies, 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy
<sup>15</sup>School of Medicine, Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, United Kingdom
<sup>1</sup>Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom, <sup>2</sup>Department of Psychology, Royal Holloway, University of London, Surrey, United Kingdom, <sup>3</sup>School of Psychology, Aston University, Birmingham, United Kingdom, <sup>4</sup>Department of Psychology, Durham University, Durham, United Kingdom, <sup>5</sup>Washington Singer Laboratories, University of Exeter, Exeter, United Kingdom, <sup>6</sup>Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom, <sup>7</sup>Johns Hopkins University, Balitmore, MD, United States, <sup>8</sup>Computer Science, University College London, London, United Kingdom, <sup>9</sup>University of Chieta-Pescara, Chieti, Italy, <sup>10</sup>School of Medicine, Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, United Kingdom
### Acknowledgements:
These data were acquired at the UK National Facility for In Vivo MR Imaging of Human Tissue Microstructure funded by the EPSRC (grant EP/M029778/1), and The Wolfson Foundation,and supported by a Wellcome Trust Investigator Award (096646/Z/11/Z) and a Wellcome Trust Strategic Award (104943/Z/14/Z).
The WAND data were acquired at the UK National Facility for In Vivo MR Imaging of Human Tissue Microstructure funded by the EPSRC (grant EP/M029778/1), and The Wolfson Foundation,and supported by a Wellcome Trust Investigator Award (096646/Z/11/Z) and a Wellcome Trust Strategic Award (104943/Z/14/Z). The UK Medical Research Council (MR/M008932/1), the Welsh Government and Cardiff University provide funding support for the CUBRIC ultra-high field imaging facility.
Olivier Mougin (University of Nottingham) developed the phase-sensitive inversion recovery and T1 code. William Clarke (Oxford University) provided the image reconstruction code for the MP2RAGE.
The authors would like to thank:
Thomos Wizel (formally MGH, now GBIO) for his help setting up the diffusion sequences on the Connectom scanner.
Olivier Mougin (University of Nottingham) for developing the phase-sensitive inversion recovery and T1 code.
William Clarke (Oxford University) for providing the image reconstruction code for the MP2RAGE.
Regarding the breath hold tasks in ses-07, four participants (listed below) completed the breath hold task with paced breathing at 1.6 s inhale, 2.4 s exhale. This pacing resulted in hyperventilation, so the participants were mildly hypocapnic. The remaining 35 participants completed the breath hold task with paced breathing at 3 s inhale, 3 s exhale and did not hyperventilate.
The four participants that were cued with the faster breathing frequency were: **sub-06400, sub-17726, sub-68412, sub-80344.**
